Solifenacin Succinate 10 mg scored tablet
Solifenacinis acompetitive cholinergic receptor antagonist, selective for the M3 receptor subtype.
he binding of acetylcholine to these receptors, particularly M3, plays a critical role in the contraction of smooth muscle. By preventing the binding of acetylcholine to these receptors, solifenacin reduces smooth muscletonein the bladder, allowing the bladder to retain larger volumes of urine and reducing the number of micturition, urgency and incontinence episodes.
once-a-day dose can offer 24-hour control of the urinary bladder smooth muscle tone
solifenacinaredry mouth, blurred vision, and constipation. As all anticholinergics, solifenacinmay rarely causehyperthermia.
e withurinary retention, gastric retention, uncontrolled or poorly controlled closed-angleglaucoma, severe liver disease.
Over Active bladder
5 –10 mg daily dose