Cipromega 0.5 MG 10 T

Composition:
extended-release tablets contain ciprofloxacin, a synthetic antimicrobial agent for oral administration.

Properties:

Cipromega 500 Xl tablets are coated, bilayer tablets consisting of an immediate-release layer and anerosion-matrix type controlled-release layer. The tablets contain a combination of two types of ciprofloxacin drug substance, ciprofloxacin hydrochloride and ciprofloxacin betaine(base).
Cipromega 500 Xl is abroad-spectrum antibioticof the fluoroquinolone class. It is active against both Gram-positive and Gram-negative bacteria. It functions by inhibitingDNA gyrase.

Spectrum of activity
•Gram-negative:

(Escherichia coli,Haemophilusinfluenzae,Klebsiellapneumoniae,Legionella pneumophila,Moraxella catarrhalis,Proteus mirabilis, andPseudomonas aeruginosa),
•Gram-positive:

(Staphylococcus aureus,Streptococcus pneumoniae,Staphylococcus epidermidis,Enterococcus faecalis, andStreptococcus pyogenes) bacterial pathogens.

Interactions
•Ciprofloxacin should not be taken with antacids containing magnesium or aluminum or with supplements containing calcium, iron, or zinc. It should be taken two hours before or six hours after these products.
•Magnesium or aluminum antacids turn ciprofloxacin into insoluble salts that are not readily absorbed by the intestinal tract, reducing peak serum concentrations by 90% or more, leading to therapeutic failure.

• dairy products or calcium-fortified juices alone, as peak serum concentration and the area under the serum concentration-time curve can be reduced up to 40%.
• However, ciprofloxacin may be taken with dairy products or calcium-fortified juices as part of a meal.

Contraindications
•Takingtizanidineat the same time
•Use by those who are hypersensitive to any member of the quinolone class of antimicrobial agents

Pregnancy
•In the United States ciprofloxacin ispregnancy categoryC.

Breastfeeding
•Fluoroquinoloneshave been reported as present in a mother’s milk and thus passed on to the nursing child.

Indications:
Un-Complicated Urinary Tract Infections
Complicated Urinary Tract Infections
Chronic Bacterial Prostatitis
Simple GIT infection
Complicated Intra–Abdominal
Infectious Diarrhea
Typhoid Fever
How Supplied:
Strips of 10 tablets, in a pack of one strip